Research Activities


Major Projects
*Protein Self assembly on the Nanoscale Surfaces
*Photodynamics and Diffusion Process involved in Sol-Gel Matrix





Recent Publications
(Journals/Book/Book Chapters)

 

 

 

 

 

K . Yokoyama (Editor) Frontiers in Nanoscience for Biomedical Research  Sign Post, in progress.

K. Yokoyama Chapter 2: Controlling Reversible Self Assembly Path by Nanoscale MetalSurface - Study of Fibrillogenesis of Alzheimmers Disease Book Chapter in Frontiers in Nanoscience for Biomedical Research Edited by K. Yokoyama (Sign Post), in progress

K. Yokoyama, Makaia Papasergi, Jeffrey Ma, Son Woung Hong, Marissa Evarts and Harold Hoops, Nano Scale Metal Surface Effect for Reversible Protein Self-Assembly, European Biophysics Journal, submitted.

K. Yokoyama Controlling Reversible Self Assembly Path of Amyloid Beta Peptide over Gold Colloidal nanoparticles Surface Book Chapter in Nanoscale Spectroscopy with Applications Edited by S. M. Musa (CRC Press-Taylor and Francis Group, LLC) in press (2013)

R. E. McKnight, D. R. Jackson, and K. Yokoyama Temperature Dependence of Congo Red Binding to Amyloid b12-28 , European Biophysics Journal, European Biophysics Journal,  Vol.42No. 6pp 495-501 (2013)

K. Yokoyama, J. Ryu, D. Mark, and J.M. Kalish, Temperature Dependence of Diffusion Process under Silica Based Sol-Gel Matrix, European Biophysics Journal, submitted.

K. Yokoyama Nano Size Dependent Properties of Colloidal Surfaces Book Chapter in Colloids: Classification, Properties and Applications Edited by P. C. Ray (Nova Science Publishing)  ISBN# 978-1-62081-128-3, pp. 25-58 (2012)

K. Yokoyama Chapter 12 “Modeling of Reversible Protein Conjugation on Nanoscale Surface” Book Chapter in “Computational Nanotechnology: Modeling and Applications with MATLAB  Sarhan M. Musa –Editor in Chief  (CRC Press-Taylor and Francis Group, LLC) (2011)  ISBN# 9781439841761 . See Book Site

K. Yokoyama  Modern Physical Chemistry for Bioscience Students -Friendly and Short Cut Guide for Physical Chemistry (2011) Linus Publication ISBN-10 1-60797-185-2  Linus Publication

K. Yokoyama, A. D. Fisher, A. R. Amori, D. R. Welchons, and R. E. McKnight, "Spectroscopic and Calorimetric Studies of Congo Red Dye-Amyloid b Peptide Complexes, J. Biophysical Chemistry,  Vol. 1 No. 3 153-163 (2010) [Journal Site]

K. Yokoyama Chapter 7 Description of solvent-dependent and nanoscale diffusion process in silica sol-gel matrix Book Chapter in Sol-Gel Process: Uniformity, Polymers and Applications.” (Nova Science Publishing) ISBN# 978-1-61761-321-0  [Book Site]

K. Yokoyama Chapter 2 "Nanoscale Protein Conjugation in Advances in Nanotechnology Vol. 1 , Eds. E. J. Chen and N. Peng (Nova Science Publishing), 2010,  ISBN978-1-60741-731-6. [Publishers Site]

K. Yokoyama, N. B. Gaulin, H. Cho, N. M. Briglio, " Temperature Dependence of Conjugation of Amyloid Beta Peptide on the Gold Colloidal Nanoparticles”, Journal of Physical Chemistry A, 114, 1521-1528 (2010). [Journal Site]

K. Yokoyama, H. Cho, S. P. Cullen, M. Kowalik, N. M. Briglio, H. J. Hoops, Z. Zhao and M. A. Carpenter " Microscopic Investigation of Reversible Nanoscale Surface Size Dependent Protein Conjugation”, International Journal of Molecular Science (Special Issue on Bioactive Nanoparticle), 10, 2348-66 (2009).[Journal Site]

K. Yokoyama J. R. Swana, T. M. Gilbert, D. D. Chen, L. Chen and P. Kogan, " The Nanoscale Description of Acid Penetration to the Gold Colloids Encapsulated in Silica Sol-Gel Matrix, Journal of Sol-Gel Science and Technology, 50, 48-57 (2009).

K. Yokoyama, N. M. Briglio, D. Sri Hartati, W. S. M. Tsang, J. E. MacCormac, and D. R. Welchons, "Nano-scale Size Dependence in the Conjugation of Amyloid Beta and Ovalbumin Proteins on the Surface of Gold Colloidal Particles, Nano-Technolog, 19, 375101-375108 (2008).[Journal Site]

D. Sri Hartati, W. Tsang, N.M. Briglio, J.E. MacCormac and K. Yokoyama, Size Dependence Of Conjugation of Amyloid Beta Protein On Gold Colloidal Nanoparticles Surfaces, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Vol. 4, 169-172 (2007)

K. Yokoyama, B. E. Johnson and J. W. Bourne, "The Photodynamics of [Ru(bpy)3]2+ Ion Dopant in a Solvent Exposed Silica Sol-gel Thin Film, Journal of Sol-Gel Science and Technology, 43, pp.259-268 (2007).

K. Yokoyama and D. R Welchons, "The Conjugation of Amyloid Beta Protein on the Gold Colloidal Nanoparticles Surface, Nano-Technology, 18(10) 105101-105107 (2007).[Journal Site]

 

 

 

 

Recent Selected Presentations






K. Yokoyama, “Controlling Reversible Self-Assembly of Amyloid beta”, Institutional Seminar, Institute for Protein Research, Osaka University, Oral Presentation, July 15, (2013) Osaka, Japan

K. Yokoyama, “Nano size colloidal surface dependent interfacial folding properties”, 245th American Chemical Society national Meeting, Oral Presentation, April 7-12, (2013) New Orleans, LA

K. Yokoyama, “Comparison of reversible self-assembly of amyloid beta (1-40) and amyloid beta (1-42) over nanoscale gold colloidal surfaces”, 245th American Chemical Society national Meeting, Oral Presentation, April 7-12, (2013) New Orleans, LA

K. Yokoyama, “Nanoscale control of diffusion process in silica based sol–gel matrix”, 245th American Chemical Society national Meeting, Oral Presentation, April 7-12, (2013) New Orleans, LA

•R. E. McKnight, D. Jackson, and K. Yokoyama, Isothermal titration calorimetric studies of the temperature dependence of Congo Red-amyloid beta 12-28 complexes”, 245th American Chemical Society national Meeting, Oral Presentation, April 7-12, (2013) New Orleans, LA

K. Yokoyama, A. L. Tran, G. T. Nguyen, “Reversible Self-Assembly of Amyloid β at Nanoscale Surface”, American Chemical Society  North East Regional Meeting, Oral presentation, Sept. 30- Oct. 3, (2012), Rochester, NY.

K. Yokoyama, “Temperature and size dependence of self-assembly of amyloid beta peptide on the colloidal nanoparticles’ surfacesl” Poster Presentation, 239th Annual Meeting of Society for Biomaterials, April 14-16 (2011), Orlando Florida.
K. Yokoyama, “Study of Nanoscale Protein Conjugation” Departmental Seminar at SUNY Brockport, Department of Chemistry October 21(2010).
K. Yokoyama, “Temperature dependence of conjugation of amyloid beta peptide on the gold colloidal nanoparticles’ surfacesl” Oral Presentation, 239th ACS national Meeting, March 25 (2010), San Francisco, CA.

K. Yokoyama, “The Nanoscale Description of Solvent Diffusion to the Gold Colloids Encapsulated in Silica Sol-Gel” Poster Presentation, NSTI Nanotech 2008, June 4 (2008) Boston, MA.

K. Yokoyama, “Size Dependence Of Conjugation of Amyloid Beta Protein On Gold Colloidal Nanoparticles’ Surfaces” Poster Presentation, NSTI Nanotech 2007, May 20-24 (2007) Santa Clara, CA.

•Tonya Gilbert and K. Yokoyama, "Investigation of Gold Colloid Nanoparticles Embedded in a Silica Based Sol-Gel", Poster Presentation 21st National Conference on Undergraduate Research, April 12-April 14 (2007), Dominican University of California, San Francisco, CA.

•Jessica MacCormac, Nicole Briglio, Dewi Sri Hartati and K. Yokoyama, "Conjugation of the Amyloid Beta Protein on the Surface of Gold Colloidal Nanoparticles", Poster Presentation, 21st National Conference on Undergraduate Research, April 12-April 14 (2007), Dominican University of California, San Francisco, CA.




$upports




External Grants

•NSF-Planning Visit to the NIMS, Japan  #52049 (2009-2011)

•NSF-Nanoscale Exploratory Research #0508240 (2005-2006)

Dreyfus Foundation Special Program in Chemistry (2002-2005)

•ACS-PRF Summer Research Fellowship #36998-G4-SF02 (2002)

•NSF-CCLI #0196409 (2001-2004)


Geneseo Internal Grants

•SUNY-Geneseo Foundation Undergraduate Research Grant (Always since 2001)-Very generous!!!

•SUNY-Geneseo Presidential Summer Fellowship 2003

•SUNY-Geneseo Research Development Scholarship 2001

 

Affiliations and etc.

 

 

American Chemical Society
Society for Biomaterial

Rochester Academy of Science
Marquis Who’s Who America

 

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