Eric Helms
Associate Professor of Chemistry
ISC 326H
585-245-5927
helms@geneseo.edu
he/him/his
Eric Helms has been a member of the Geneseo faculty since 2001. He was awarded the Chancellor’s Award for Excellence in Teaching in 2014.

Fall 2025 Office Hours
Curriculum Vitae
Education
Ph.D., University of Texas at Austin, Austin, Texas
B.S., Rockford College, Rockford, Illinois
Publications
Nicolas Elia, Eric D. Helms; “A green method for the direct precipitation of 3-methylpyrido[2,3-b]pyrazin-2(1H)-one and 2-methylpyrido[3,4-b]pyrazin-3(4H)-one from ethyl lactate solutions”; Tetrahedron Green Chem, Volume 6, 2025, 100083. https://doi.org/10.1016/j.tgchem.2025.100083
Coffey, J. M., Vadas, A., Puleo, Y., Lewis, K., Pirone, G., Rudolf, H.L., Helms, E.D., Wood, T. D., and Flynn- Charlebois, A.; “Synthesis and Characterization of a Deuterium-Labeled Stercobilin: A Potential Biomarker for Autism”, Journal of Labelled Compounds and Radiopharmaceuticals, 2018; 14 May, 1–7. https://doi.org/10.1002/jlcr.3629
Hilimire, Thomas; Chamberlain, Jeffrey; Anokhina, Viktoriya; Bennett, Ryan; Swart, Oliver; Myers, Jason; Ashton, John; Stewart, Ryan; Gates, Kathleen; Featherston, Aaron; Helms, Eric; Smith, Harold; Dewhurst, Stephen; Miller, Benjamin; “HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi Drug-Resistant HIV in Human Cells”, Publication Date (Web): April 27, 2017 (Articles) DOI: 10.1021/acschembio.7b00052.
Best, Katherine T., Li, Diana, Helms, Eric D.; “Molecular Modeling of an Electrophilic Addition Reaction with ‘Unexpected’ Regiochemisty” The Journal of Chemical Education, 2017, 94(7), 936 – 940. DOI: 10.1021/acs.jchemed.6b00488. Publication Date (Web) April 27, 2017.
Hilimire TA, Bennett RP, Stewart RA, Garcia-Miranda P, Blume A, Becker J, Sherer N, Helms ED, Butcher SE, Smith HC, Miller BL.; “N-Methylation as a Strategy for Enhancing the Affinity and Selectivity of RNA-binding Peptides: Application to the HIV-1 Frameshift-Stimulating RNA”; ACS Chemical Biology, 2016, 11(1), 88 – 94.
Swoger, Bonnie J.M..; Helms, E.; “An Organic Chemistry Exercise in Information Literacy Using SciFinder”; Journal of Chemical Education, 2015, 92 (4), 668–671.
Arpaia, N.; Widener, M.; Helms, E.; “Assigning the NMR Spectrum of Glycidol: An Advanced Organic Chemistry Exercise”; Journal of Chemical Education, 2007, 84(8), 1328 – 1330.
Odenbaugh, Amy L. , Helms, Eric D., Iverson, Brent L.; “An Investigation of Antibody Acyl Hydrolysis Catalysis Using a Large Set of Related Haptens”; Bioorganic and Medicinal Chemistry, 2000, 8, 413-426.
Shreder, K., Thomas, R., Wallace, M., Helms, E., Iverson, B.; “Evolution of Catalytic Activity throughout a Polyclonal Immune Response Elicited by a Transition-State-Analog Hapten.”; Isr. J. Chem., 1996, 36, 215-220.
Interests
Research Interests
Developing green synthetic pathways, utilizing bio-derived and bio-degradable solvents, with an eye toward producing useful molecules without petroleum-derived solvents.
Personal Interests
- Bioorganic Chemistry, Natural Products Chemistry, Green Chemistry, Functional Foods
