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Eric Helms

Associate Professor of Chemistry
ISC 326H
585-245-5927
helms@geneseo.edu

Eric Helms has been a member of the Geneseo faculty since 2001; He was awarded the Chancellor's Award for Excellence in Teaching in 2014.

 

Office Hours

Regular office hours are Thursdays from 1:30 - 4 pm and Fridays from 2 - 4:30 pm. Biochemistry Program office hours are Thursdays from 11:30 - 1 pm. 

Other times by appointment are available, or just drop by - if my door is open you are welcome to come in and chat.

Curriculum Vitae

Education

  • Ph.D., University of Texas at Austin, Austin, Texas

  • B.S., Rockford College, Rockford, Illinois

Publications

  • Coffey, J. M., Vadas, A., Puleo, Y., Lewis, K., Pirone, G., Rudolf, H.L., Helms, E.D., Wood, T. D., and Flynn- Charlebois, A.; “Synthesis and Characterization of a Deuterium-Labeled Stercobilin: A Potential Biomarker for Autism”, Journal of Labelled Compounds and Radiopharmaceuticals, 2018; 14 May, 1–7. https://doi.org/10.1002/jlcr.3629

  • Hilimire, Thomas; Chamberlain, Jeffrey; Anokhina, Viktoriya; Bennett, Ryan; Swart, Oliver; Myers, Jason; Ashton, John; Stewart, Ryan; Gates, Kathleen; Featherston, Aaron; Helms, Eric; Smith, Harold; Dewhurst, Stephen; Miller, Benjamin; “HIV-1 Frameshift RNA-Targeted Triazoles Inhibit Propagation of Replication-Competent and Multi Drug-Resistant HIV in Human Cells”, Publication Date (Web): April 27, 2017 (Articles) DOI: 10.1021/acschembio.7b00052.

  • Best, Katherine T., Li, Diana, Helms, Eric D.; “Molecular Modeling of an Electrophilic Addition Reaction with ‘Unexpected’ Regiochemisty” The Journal of Chemical Education, 2017, 94(7), 936 – 940. DOI: 10.1021/acs.jchemed.6b00488. Publication Date (Web) April 27, 2017.

  • Hilimire TA, Bennett RP, Stewart RA, Garcia-Miranda P, Blume A, Becker J, Sherer N, Helms ED, Butcher SE, Smith HC, Miller BL.; “N-Methylation as a Strategy for Enhancing the Affinity and Selectivity of RNA-binding Peptides: Application to the HIV-1 Frameshift-Stimulating RNA”; ACS Chemical Biology, 2016, 11(1), 88 – 94.

  • Swoger, Bonnie J.M..; Helms, E.; “An Organic Chemistry Exercise in Information Literacy Using SciFinder”; Journal of Chemical Education, 2015, 92 (4), 668–671.

  • Arpaia, N.; Widener, M.; Helms, E.; "Assigning the NMR Spectrum of Glycidol: An Advanced Organic Chemistry Exercise"; Journal of Chemical Education, 2007, 84(8), 1328 - 1330.

  • Odenbaugh, Amy L. , Helms, Eric D., Iverson, Brent L.; "An Investigation of Antibody Acyl Hydrolysis Catalysis Using a Large Set of Related Haptens"; Bioorganic and Medicinal Chemistry, 2000, 8, 413-426.

  • Shreder, K., Thomas, R., Wallace, M., Helms, E., Iverson, B.; "Evolution of Catalytic Activity throughout a Polyclonal Immune Response Elicited by a Transition-State-Analog Hapten."; Isr. J. Chem., 1996, 36, 215-220.

Interests

Research Interests

Analyzing the phytochemistry of Elaeagnus umbellata fruits as they mature over a growing season as well as the phytochemistry of the leaves and stems.

Developing a genetic test to differentiate the different members of the Elaeagnus genus in order to produce a rapid identification assay.

Developing green synthetic pathways, utilizing bio-derived and bio-degradable solvents, with an eye toward producing useful molecules without petroleum-derived solvents.

 

Personal Interests

  • Bioorganic Chemistry, Natural Products Chemistry, Green Chemistry, Functional Foods

Classes

  • CHEM 211: Organic Chemistry I

    An introduction to modern organic chemistry using a functional group approach. Topics include structure/reactivity relationships, reaction mechanisms, stereochemistry, and spectroscopy. Prerequisites: CHEM 118 or CHEM 204, CHEM 119. Offered every fall

  • CHEM 216: Organic Chemistry Laboratory

    Laboratory practices in representative organic preparations and procedures. Prerequisites: /Corequisite: CHEM 211 or CHEM 223. Offered every fall and spring

  • CHEM 224: Principles of Organic Chem II

    Continuation of CHEM 223 with emphasis on the biochemically important alcohol, amine, carbonyl and aromatic fuctional groups. Structure elucidation by spectroscopic methods is also explored. Prerequisites: CHEM 211 or CHEM 223. Offered every fall.