Yokoyama Research Group Helps Fight Alzheimer's Disease

Kazu Yokoyama
Professor Kazushige Yokoyama (SUNY Geneseo/Keith Walters '11)
Chemistry News

Chemistry Professor Dr. Kazushige Yokoyama is driven to understand the biophysical processes associated with the formation of Alzheimer's Disease (AD) plaques, with the hope of one day helping contribute to a cure. Dr. Yokoyama and co-workers recently authored an article, Protein Corona Formation and Aggregation of Amyloid β 1–40-Coated Gold Nanocolloids, that takes one step towards this goal. Utilizing a cutting edge known as a surface enhance Raman spectroscopy, Dr. Yokoyama discovered specific chemical interactions that may be involved in early stages of AD plaque formation.

The work features six Geneseo undergraduate co-authors was included in a special edition of the journal dedicated to Bettye Washington Green, one of the first African American women to earn a Ph.D. in Chemistry in the United States, and the first African American female Research Scientist at The Dow Chemical Company.

Learn more about the research article, the Chemistry Department and undergraduate research at Geneseo.



Kazushige Yokoyama, Eli Barbour, Rachel Hirschkind, Bryan Martinez Hernandez, Kaylee Hausrath, and Theresa Lam. ”Protein Corona Formation and Aggregation of Amyloid β 1–40-Coated Gold Nanocolloids,” Langmuir 2024 40 (3), 1728-1746 DOI: 10.1021/acs.langmuir.3c02923